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维生素证据充分

Folate

别名: folic acid, vitamin B9, 5-MTHF

Folate (vitamin B9) is needed for cell division, DNA and blood formation and for converting homocysteine. Women planning a pregnancy are advised to take folic acid before conception to prevent neural tube defects in the baby.

用途

  • Prevention of neural tube defects when taken before conception and in early pregnancy – strong evidence (WHO, EFSA)
  • Normal blood formation and reduced tiredness – strong evidence (EFSA)
  • Lowering homocysteine together with B6 and B12 – strong evidence, though the heart benefit is unclear

剂型及区别

folic acid

synthetic form with the most evidence in pregnancy

5-MTHF (methylfolate, active folate)

active form the body does not need to convert; a suitable alternative

folic acid with B12

sensible combination – folate can mask B12 deficiency

何时服用

Once daily, with or without food.

适合搭配

Vitamin B12, vitamin B6.

不宜同服 / 需错开

Do not take high-dose folic acid without checking your B12 level.

注意事项

If you take medicines (e.g. methotrexate, antiepileptics), folate can affect their action – consult your doctor. Discuss the dose in pregnancy and when planning it with your gynaecologist.

安全性

EFSA set an upper limit of 1000 µg synthetic folic acid (or methylfolate) per day for adults; folate from food does not count.

实用建议

If you are planning a pregnancy, start folate at least one month before conception.

含 Folate 的产品 12

Folate (6S)-5-methyltetrahydrofolate glucosamine salt 400 µg(6S)-5-methyltetrahydrofolate glucosamine salt · 400 µg / 粒造血女性健康生育情绪
Folate + Omega-3 fatty acidsfolic acid + algal DHA造血女性健康生育情绪
Folate folic acid (pteroylmonoglutamic acid) 800 µgfolic acid (pteroylmonoglutamic acid) · 800 µg / 片造血女性健康生育情绪
Folate folic acid + B12 800 µgfolic acid + B12 · 800 µg / 片造血女性健康生育情绪
Folate methylfolatemethylfolate造血女性健康生育情绪
Folate 1000 µgL-methylfolate (5-MTHF) · 1 000 µg / 粒造血女性健康生育情绪
Folate 400 µgL-methylfolate (5-MTHF) · 400 µg / 粒造血女性健康生育情绪
Folate 600 µgL-methylfolate (5-MTHF) · 600 µg / 粒造血女性健康生育情绪
Inositol + Folatepowder女性健康激素血糖与代谢生育
Vitamin B12 + Folate 1000 µgmethylcobalamin + methylfolate · 1 000 µg / 片造血精力大脑与记忆情绪
Vitamin B12 + Folate 5000 µgmethylcobalamin + methylfolate · 5 000 µg / 片造血精力大脑与记忆情绪
Iron + Folatechelate造血精力大脑与记忆女性健康
如何理解证据评级
证据充分证据中等证据薄弱无证据

充分 = 多项高质量人体研究或官方推荐;中等 = 有前景但研究规模较小;薄弱 = 研究少或结果不一;无证据 = 说法未被证实。

搭配检查

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检查 Folate 与其他的搭配

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重要提示

以上信息仅供科普,不能替代医生或药师建议,我们不提供药物剂量。补充剂不能替代均衡饮食;孕期、哺乳期、患病或服药者请先咨询医生。