Order protocol
Sleep & recovery Whole topic
Hormones & energy Whole topic
Metabolism & nutrition Whole topic
Brain & mind Whole topic
Longevity & body Whole topic
Women & family Whole topic
Basics & environment Whole topic
Biohacking & technology Whole topic
Fénix Methode

Tired of generic advice? A protocol built on your numbers.

Order protocol
All articles Every article is based on a chapter of the book NAVRHNUTÝ and peer-reviewed studies.
Biohacker score2 minutes – find out where your body holds you back Results checkNormal vs. optimal for your blood values Biological ageHow old your body is – from 9 blood values CalculatorsBMI, waist, protein, sleep, caffeine, VO2max Daily helperDaily routines, light, sleep and breathing on your phone My stackCheck supplements & medication + daily plan ChallengesSmall daily habits with reminders Fitness testVO2max, fitness age, strength and balance at home Biological twinAll your data in a 3D body What to get testedPrintable list of blood tests Sample protocolSee what you get E-numbers & sugarsWhat is on the label and what to avoid Online advisorAnswers to common questions about body and results SupplementsForms, timing and combination check RecipesMeals without hidden sugars or needless additives GlossaryBiohacking explained from A to Z Gift voucherGive health – the protocol or the book
← All supplements
VitaminsStrong evidence

Folate

Also known as: folic acid, vitamin B9, 5-MTHF

Folate (vitamin B9) is needed for cell division, DNA and blood formation and for converting homocysteine. Women planning a pregnancy are advised to take folic acid before conception to prevent neural tube defects in the baby.

What it is used for

  • Prevention of neural tube defects when taken before conception and in early pregnancy – strong evidence (WHO, EFSA)
  • Normal blood formation and reduced tiredness – strong evidence (EFSA)
  • Lowering homocysteine together with B6 and B12 – strong evidence, though the heart benefit is unclear

Forms and how they differ

folic acid

synthetic form with the most evidence in pregnancy

5-MTHF (methylfolate, active folate)

active form the body does not need to convert; a suitable alternative

folic acid with B12

sensible combination – folate can mask B12 deficiency

When to take it

Once daily, with or without food.

Pairs well with

Vitamin B12, vitamin B6.

Do not combine / separate

Do not take high-dose folic acid without checking your B12 level.

Watch out for

If you take medicines (e.g. methotrexate, antiepileptics), folate can affect their action – consult your doctor. Discuss the dose in pregnancy and when planning it with your gynaecologist.

Safety

EFSA set an upper limit of 1000 µg synthetic folic acid (or methylfolate) per day for adults; folate from food does not count.

Practical tip

If you are planning a pregnancy, start folate at least one month before conception.

Products containing Folate 12

Folate (6S)-5-methyltetrahydrofolate glucosamine salt 400 µg(6S)-5-methyltetrahydrofolate glucosamine salt · 400 µg / capsuleBlood formationWomen’s healthFertilityMood
Folate + Omega-3 fatty acidsfolic acid + algal DHABlood formationWomen’s healthFertilityMood
Folate folic acid (pteroylmonoglutamic acid) 800 µgfolic acid (pteroylmonoglutamic acid) · 800 µg / tabletBlood formationWomen’s healthFertilityMood
Folate folic acid + B12 800 µgfolic acid + B12 · 800 µg / tabletBlood formationWomen’s healthFertilityMood
Folate methylfolatemethylfolateBlood formationWomen’s healthFertilityMood
Folate 1000 µgL-methylfolate (5-MTHF) · 1 000 µg / capsuleBlood formationWomen’s healthFertilityMood
Folate 400 µgL-methylfolate (5-MTHF) · 400 µg / capsuleBlood formationWomen’s healthFertilityMood
Folate 600 µgL-methylfolate (5-MTHF) · 600 µg / capsuleBlood formationWomen’s healthFertilityMood
Inositol + FolatepowderWomen’s healthHormonesBlood sugar & metabolismFertility
Vitamin B12 + Folate 1000 µgmethylcobalamin + methylfolate · 1 000 µg / tabletBlood formationEnergyBrain & memoryMood
Vitamin B12 + Folate 5000 µgmethylcobalamin + methylfolate · 5 000 µg / tabletBlood formationEnergyBrain & memoryMood
Iron + FolatechelateBlood formationEnergyBrain & memoryWomen’s health
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence

Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.

Combination check

Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.

Check Folate with others

Which supplements do you actually need?

Fénix Methode picks them from your blood results and schedules when to take what – no needless purchases.

Learn about Fénix Methode

From the same group

B complexModerate evidenceBeta-caroteneWeak evidenceBiotinWeak evidenceBrewer's yeastWeak evidenceCamu camuWeak evidenceCholineModerate evidence
Important notice

This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.