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VitaminsModerate evidence

Vitamins ADEK

Also known as: fat-soluble vitamin complex

Vitamins ADEK combine the four fat-soluble vitamins – A, D, E and K – in one capsule. They are used mainly with fat malabsorption (e.g. cystic fibrosis, pancreatic disease or after bowel surgery), where deficiency of these vitamins is common.

What it is used for

  • Prevention of vitamin A, D, E and K deficiency with fat malabsorption – moderate evidence
  • Bone, immune and vision support – strong evidence for the role of each vitamin (EFSA)
  • Benefit for healthy people on a varied diet – weak evidence

Forms and how they differ

ADEK complex

typically vitamin A (retinol or beta-carotene), D3, E and K1 or K2; quality and doses depend on the label

When to take it

With a meal containing fat.

Pairs well with

With malabsorption, digestive enzymes as advised by your doctor.

Do not combine / separate

Do not combine with other vitamin A, D, E or K products – doses add up.

Watch out for

In pregnancy watch the vitamin A content. If you take warfarin-type blood thinners (vitamin K antagonists), vitamin K changes their effect – use it only after agreeing with your doctor. With other blood thinners, in pregnancy and with liver disease also consult your doctor.

Safety

Respect EFSA limits: vitamin A 3000 µg, vitamin D 100 µg (4000 IU), vitamin E 300 mg per day – from all sources combined.

Practical tip

Without malabsorption, usually a targeted vitamin D supplement in winter is enough.

Products containing Vitamins ADEK 1

Vitamins ADEK retinyl palmitate + cholecalciferol + tocopheryl acetate + K1/K2 1000 IUretinyl palmitate + cholecalciferol + tocopheryl acetate + K1/K2 · 1 000 IU / capsuleBonesImmunityEyesAntioxidant
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence

Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.

Combination check

Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.

Check Vitamins ADEK with others

Which supplements do you actually need?

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Important notice

This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.