When to take it
In the morning with food, long term.
← All supplements
LongevityWeak evidence
Spermidine
Also known as: polyamine, wheat germ extract
Spermidine is a natural polyamine found in wheat germ, soy, mushrooms and aged cheese that promotes autophagy – the cellular clean-up of damaged parts. Animal experiments are promising, but human data are still limited.
What it is used for
- Support for autophagy and healthy ageing – weak evidence, mainly from animal and observational studies
- Memory in older adults – weak evidence, results are mixed
- Hair growth – weak evidence
Forms and how they differ
wheat germ extract
the most common form in the EU, contains gluten unless stated otherwise
synthetic spermidine
less common, quality depends on the label
Pairs well with
A diet with wheat germ, legumes, mushrooms and whole grains; intermittent fasting.
Do not combine / separate
No significant interactions are known.
Watch out for
With coeliac disease check whether the extract contains gluten. In pregnancy, while breastfeeding, with cancer, kidney or liver disease and when taking medicines, consult your doctor.
Safety
Do not exceed the label dose.
Practical tip
A spoonful of wheat germ in porridge provides spermidine more cheaply than capsules.
Products containing Spermidine 3
Spermidine wheat germ extractwheat germ extract
Spermidinepowder
Spermidine 2.5 mgchlorella/wheat germ source · 2.5 mg / capsule
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence
Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.
Combination check
Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.
Check Spermidine with othersWhich supplements do you actually need?
Fénix Methode picks them from your blood results and schedules when to take what – no needless purchases.
From the same group
Agaricus blazeiWeak evidenceAlpha-lipoic acidModerate evidenceAstaxanthinWeak evidenceCoenzyme Q10Moderate evidenceDNA protection blendNo evidenceErgothioneineWeak evidence
Important notice
This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.