When to take it
With food, once a day.
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LongevityWeak evidence
Ergothioneine
Also known as: L-ergothioneine, mushroom antioxidant
Ergothioneine is an amino-acid antioxidant made by fungi and some bacteria that the human body cannot produce. The body nevertheless absorbs it actively via its own transporter and stores it in tissues, which has led to hypotheses about a protective role.
What it is used for
- Antioxidant protection of cells – weak evidence, data mainly from laboratory and animal studies
- Association with slower cognitive ageing – weak evidence, observational studies only
Forms and how they differ
L-ergothioneine (capsules)
the pure compound, authorised in the EU as a novel food
mushroom extracts
a natural source, ergothioneine content is often not stated
Pairs well with
Mushrooms in the diet (oyster, shiitake, porcini), a varied diet.
Do not combine / separate
No significant interactions are known.
Watch out for
Data on long-term use are limited. In pregnancy, while breastfeeding, with kidney or liver disease and when taking medicines, consult your doctor.
Safety
Do not exceed the label dose.
Practical tip
Oyster mushrooms and porcini are among the richest food sources of ergothioneine.
Products containing Ergothioneine 1
Ergothioneine
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence
Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.
Combination check
Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.
Check Ergothioneine with othersWhich supplements do you actually need?
Fénix Methode picks them from your blood results and schedules when to take what – no needless purchases.
From the same group
Agaricus blazeiWeak evidenceAlpha-lipoic acidModerate evidenceAstaxanthinWeak evidenceCoenzyme Q10Moderate evidenceDNA protection blendNo evidenceGlutathioneWeak evidence
Important notice
This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.