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LongevityWeak evidence

Glutathione

Also known as: GSH, reduced glutathione

Glutathione is the main intracellular antioxidant, made by the body from cysteine, glycine and glutamate. When taken by mouth, part of it is broken down in the gut, so its effect is uncertain.

What it is used for

  • Raising blood glutathione – weak to moderate evidence with long-term use
  • Liver support – weak evidence
  • Skin lightening – weak evidence

Forms and how they differ

reduced glutathione (GSH)

common capsule form

liposomal glutathione

meant to improve absorption; evidence is limited

S-acetyl glutathione

more stable form, few studies

precursors (NAC + glycine)

cheaper option to support your own production

When to take it

On an empty stomach or between meals, in the morning.

Pairs well with

Works well with vitamin C and selenium.

Do not combine / separate

During chemotherapy, do not combine with antioxidants without your oncologist's approval.

Watch out for

Not recommended in pregnancy or breastfeeding due to lack of data. If you have asthma (inhaled forms), are in cancer treatment, have liver or kidney disease or take medicines, consult your doctor.

Safety

Generally well tolerated at usual doses. Do not exceed the label dose.

Practical tip

Support your own glutathione with food too – broccoli, garlic, onions and enough protein.

Products containing Glutathione 6

Glutathione reduced glutathionereduced glutathioneAntioxidantLiverSkinLongevity
Glutathione + Ceramides (phytoceramides)blendAntioxidantLiverSkinLongevity
Glutathione + L-cysteine + Vitamin CmixedAntioxidantLiverSkinLongevity
Glutathione 100 mgreduced L-glutathione · 100 mg / capsuleAntioxidantLiverSkinLongevity
Glutathione 250 mg250 mg / capsuleAntioxidantLiverSkinLongevity
GlutathioneliposomalAntioxidantLiverSkinLongevity
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence

Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.

Combination check

Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.

Check Glutathione with others

Which supplements do you actually need?

Fénix Methode picks them from your blood results and schedules when to take what – no needless purchases.

Learn about Fénix Methode

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Important notice

This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.