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LongevityWeak evidence

Pine bark extract

Also known as: maritime pine, Pinus pinaster, OPC, proanthocyanidins

Maritime pine bark extract is rich in proanthocyanidins (OPC) and other polyphenols. It is studied mainly for supporting blood vessels, circulation and skin.

What it is used for

  • Support for circulation and blood-vessel function – weak to moderate evidence
  • Modest blood pressure reduction – weak evidence
  • Skin hydration and elasticity – weak evidence
  • Relief of chronic venous insufficiency symptoms – weak evidence

Forms and how they differ

standardised extract (OPC)

check the proanthocyanidin percentage, most often 65–75%

grape seed extract

a similar group of compounds (OPC) from a different source

When to take it

With food, once or twice a day.

Pairs well with

Vitamin C, a polyphenol-rich diet, exercise.

Do not combine / separate

Be careful with anticoagulants, blood-pressure and diabetes medicines, and immunosuppressants.

Watch out for

Not well studied in pregnancy and breastfeeding. With autoimmune, kidney or liver disease and when taking medicines, consult your doctor.

Safety

Do not exceed the label dose.

Practical tip

Judge the effect on circulation by measuring blood pressure at home before you start and after 2 months.

Products containing Pine bark extract 4

Pine bark extract OPC 240 mgOPC · 240 mg / capsuleHeart & vesselsAntioxidantSkinBrain & memory
Pine bark extract 380 mgwhole seed powder · 380 mg / capsuleHeart & vesselsAntioxidantSkinBrain & memory
Pine bark extract 100 mgPycnogenol · 100 mg / capsuleHeart & vesselsAntioxidantSkinBrain & memory
Pine bark extract 150 mgPycnogenol · 150 mg / capsuleHeart & vesselsAntioxidantSkinBrain & memory
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence

Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.

Combination check

Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.

Check Pine bark extract with others

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From the same group

Agaricus blazeiWeak evidenceAlpha-lipoic acidModerate evidenceAstaxanthinWeak evidenceCoenzyme Q10Moderate evidenceDNA protection blendNo evidenceErgothioneineWeak evidence
Important notice

This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.