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Fénix Methode

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Amino acidsNo evidence

Dimethylglycine

Also known as: DMG, N,N-dimethylglycine

Dimethylglycine (DMG) is a derivative of the amino acid glycine that forms in the body when betaine is converted to methionine. It is sold for endurance, immunity and as a "methyl donor", but good human evidence is lacking.

What it is used for

  • endurance and oxygen use in sport – no reliable evidence
  • immune support – weak evidence, older small studies
  • methylation support – theoretical, no clinical evidence

Forms and how they differ

DMG tablets or capsules

usually low doses, sometimes sublingual

betaine (TMG)

a better-studied alternative for homocysteine metabolism

When to take it

With food or as the label says.

Pairs well with

Folate, vitamin B12, vitamin B6.

Do not combine / separate

No known serious interactions, but do not stack several "methylation" supplements without a reason.

Watch out for

Not suitable in pregnancy or breastfeeding due to lack of data. With chronic illness or when taking medicines, consult your doctor.

Safety

Long-term safety data are limited; do not exceed the label dose.

Practical tip

If homocysteine is your concern, betaine (TMG) and B vitamins have better evidence than DMG.

Products containing Dimethylglycine 1

Dimethylglycine 125 mgDMG · 125 mg / capsuleEnergyEnduranceImmunity
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence

Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.

Combination check

Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.

Check Dimethylglycine with others

Which supplements do you actually need?

Fénix Methode picks them from your blood results and schedules when to take what – no needless purchases.

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From the same group

Acetyl-L-carnitineWeak evidenceAlmond proteinWeak evidenceAmino acid complexWeak evidenceBCAAWeak evidenceBeef proteinModerate evidenceCaseinStrong evidence
Important notice

This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.