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VitaminsWeak evidence

Vitamin B5

Also known as: pantothenic acid, pantethine

Vitamin B5 is part of coenzyme A, which is key for fat metabolism and the production of energy and stress hormones. It is found in almost all foods, so deficiency is very rare.

What it is used for

  • Normal energy metabolism and mental performance – strong evidence for the basic role (EFSA)
  • Pantethine for modestly lowering LDL cholesterol and triglycerides – weak to moderate evidence from smaller studies
  • Acne and stress management – weak evidence

Forms and how they differ

calcium or sodium D-pantothenate

standard forms in multivitamins

pantethine

active form studied for blood lipids, at higher doses

When to take it

With food.

Pairs well with

Other B vitamins.

Do not combine / separate

No significant interactions with supplements.

Watch out for

If you use pantethine for cholesterol and also take lipid-lowering or blood-thinning medicines, consult your doctor. In pregnancy only after agreeing with your doctor.

Safety

EFSA has not set an upper limit; high doses may cause diarrhoea. Do not exceed the label dose.

Practical tip

A varied diet covers everyday B5 needs – a separate supplement only makes sense for targeted pantethine use.

Products containing Vitamin B5 8

Vitamin B5 pantothenic acidpantothenic acidEnergyStressSkin
Vitamin B5 pantethine 300 mgpantethine · 300 mg / capsuleEnergyStressSkin
Vitamin B5 600 mgpantethine · 600 mg / capsuleEnergyStressSkin
Vitamin B5 200 mgcalcium pantothenate · 200 mg / capsuleEnergyStressSkin
Vitamin B5 350 mgcalcium pantothenate · 350 mg / capsuleEnergyStressSkin
Vitamin B5 sodium D-pantothenate 18 mgsodium D-pantothenate · 18 mg / capsuleEnergyStressSkin
Vitamin B5 500 mgcalcium pantothenate · 500 mg / capsuleEnergyStressSkin
Vitamin B5 pantethine 10 mgpantethine · 10 mg / capsuleEnergyStressSkin
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence

Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.

Combination check

Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.

Check Vitamin B5 with others

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From the same group

B complexModerate evidenceBeta-caroteneWeak evidenceBiotinWeak evidenceBrewer's yeastWeak evidenceCamu camuWeak evidenceCholineModerate evidence
Important notice

This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.