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Fénix Methode

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← All supplements
Amino acidsWeak evidence

L-tryptophan

Also known as: tryptophan

Tryptophan is an essential amino acid the body uses to make serotonin and melatonin. Supplements are used mainly to support sleep and mood.

What it is used for

  • Faster sleep onset – weak evidence
  • Mood support – weak evidence

Forms and how they differ

L-tryptophan

standard form in capsules and powder

When to take it

In the evening 30–60 minutes before bed, ideally with a carbohydrate snack low in protein.

Pairs well with

Vitamin B6, magnesium.

Do not combine / separate

Do not combine with 5-HTP, St John's wort or other serotonin-raising substances.

Watch out for

Do not take with antidepressants (SSRIs, MAOIs and others), triptans or sleep medication without your doctor's approval – risk of serotonin syndrome. Consult your doctor or pharmacist if you are pregnant, breastfeeding, have kidney or liver disease or take any medicines.

Safety

Do not exceed the label dose.

Practical tip

Try the sleep basics first – a regular bedtime and a dark bedroom.

Products containing L-tryptophan 4

L-tryptophanSleepMood
L-tryptophan 1000 mgfree form · 1 000 mg / tabletSleepMood
L-tryptophan 430 mgfree form · 430 mg / capsuleSleepMood
L-tryptophan free form 500 mgfree form · 500 mg / capsuleSleepMood
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence

Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.

Combination check

Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.

Check L-tryptophan with others

Which supplements do you actually need?

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From the same group

Acetyl-L-carnitineWeak evidenceAlmond proteinWeak evidenceAmino acid complexWeak evidenceBCAAWeak evidenceBeef proteinModerate evidenceCaseinStrong evidence
Important notice

This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.