When to take it
In the morning, with or without food.
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LongevityWeak evidence
Nicotinamide riboside
Also known as: NR, NAD+ precursor, a form of vitamin B3
Nicotinamide riboside is a form of vitamin B3 that the body turns into the coenzyme NAD+, important for energy production and DNA repair. NAD+ levels decline with age, which is why NR is studied as a supplement for healthy ageing.
What it is used for
- Raising blood NAD+ levels – moderate evidence
- Improving health, energy or ageing in humans – weak evidence, results so far are modest
Forms and how they differ
nicotinamide riboside chloride
the form authorised in the EU as a novel food
NMN (nicotinamide mononucleotide)
a related NAD+ precursor with similarly limited evidence
NR + Q10 and other combinations
quality depends on the label
Pairs well with
Exercise, sleep and a protein-sufficient diet – these also raise NAD+.
Do not combine / separate
Do not combine with other high doses of vitamin B3 (niacin, nicotinamide).
Watch out for
Not suitable in pregnancy or while breastfeeding (insufficient data). With liver or kidney disease, cancer and when taking medicines, consult your doctor.
Safety
EFSA considers up to 300 mg a day safe for adults; do not exceed the label dose.
Practical tip
It is an expensive supplement with uncertain benefit – exercise and sleep remain the foundation.
Products containing Nicotinamide riboside 4
NADH / NAD+ + Nicotinamide riboside 750 mgnicotinamide riboside blend · 750 mg / capsule
Nicotinamide riboside + CoQ10+ CoQ10
Nicotinamide riboside 100 mgNR chloride · 100 mg / capsule
Nicotinamide riboside 300 mgNR chloride · 300 mg / capsule
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence
Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.
Combination check
Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.
Check Nicotinamide riboside with othersWhich supplements do you actually need?
Fénix Methode picks them from your blood results and schedules when to take what – no needless purchases.
From the same group
Agaricus blazeiWeak evidenceAlpha-lipoic acidModerate evidenceAstaxanthinWeak evidenceCoenzyme Q10Moderate evidenceDNA protection blendNo evidenceErgothioneineWeak evidence
Important notice
This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.