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PerformanceModerate evidence

Guarana

Also known as: Paullinia cupana, guarana powder

Guarana is a South American vine whose seeds contain more caffeine than coffee beans, along with theobromine and tannins. Its effect on alertness and performance mainly reflects its caffeine content.

What it is used for

  • alertness and focus – moderate evidence, effect attributed to caffeine
  • endurance performance – moderate evidence for caffeine
  • weight loss support – weak evidence

Forms and how they differ

seed powder

caffeine content varies and is often not stated

extract standardised to caffeine

more precise dosing

tincture

contains alcohol, caffeine content is harder to estimate

When to take it

In the morning or before training; not later than 6–8 hours before bed.

Pairs well with

L-theanine for a 'smoother' energy, plenty of water.

Do not combine / separate

Do not combine with coffee, energy drinks or other caffeine sources without adding up the total dose; keep a gap from iron and thyroid medicines.

Watch out for

During pregnancy and breastfeeding, limit total caffeine. With high blood pressure, heart rhythm disorders, anxiety, insomnia, kidney or liver disease, or if you take medicines (especially stimulants, some antidepressants, asthma medicines), consult your doctor.

Safety

EFSA considers up to 400 mg caffeine per day and up to 200 mg at once safe for healthy adults; up to 200 mg per day during pregnancy. Add up all caffeine sources and do not exceed the label dose.

Practical tip

Look for products that state caffeine in mg per dose – otherwise you cannot tell how much you are really taking.

Products containing Guarana 3

Guarana 500 mgseed powder · 500 mg / capsuleEnergyFocusEndurance
Guaranaseed powderEnergyFocusEndurance
GuaranatinctureEnergyFocusEndurance
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence

Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.

Combination check

Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.

Check Guarana with others

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Important notice

This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.