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Fénix Methode

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← All supplements
OtherWeak evidence

Glucosamine

Also known as: glucosamine sulfate, glucosamine HCl

Glucosamine is an amino sugar the body uses to build cartilage and joint fluid; in supplements it is made from shellfish shells or by fermentation. It is used mainly for knee osteoarthritis, but study results are mixed.

What it is used for

  • Pain relief in knee osteoarthritis – weak evidence, best results with crystalline glucosamine sulfate
  • Slower cartilage loss – weak evidence

Forms and how they differ

glucosamine sulfate (2KCl / NaCl)

most studied, stabilised with salt

glucosamine HCl

more concentrated but weaker evidence

vegetarian glucosamine

from corn fermentation, suitable with shellfish allergy

glucosamine + chondroitin

a common combination, quality depends on the label

When to take it

With food, daily and long term; any effect usually appears after 4–8 weeks.

Pairs well with

Chondroitin, exercise and thigh strengthening, keeping a healthy weight.

Do not combine / separate

Be careful with warfarin and other anticoagulants (possible increased effect).

Watch out for

With shellfish allergy choose the vegetarian form. With diabetes, asthma, in pregnancy, with kidney or liver disease and when taking medicines (especially anticoagulants), consult your doctor. Salt forms contain sodium or potassium.

Safety

Do not exceed the label dose.

Practical tip

If you feel no improvement after 3 months, continuing probably makes little sense.

Products containing Glucosamine 8

Glucosamine + chondroitin+ chondroitinJointsInflammation
Glucosamine + chondroitin + MSM+ chondroitin + MSMJointsInflammation
Glucosamine + ChondroitinsulfatesJointsInflammation
Glucosamine vegetarian (HCl) 1000 mgvegetarian (HCl) · 1 000 mg / capsuleJointsInflammation
Glucosamine sulfate 2KCl 1 gsulfate 2KCl · 1 g / servingJointsInflammation
Glucosamine sulfatesulfateJointsInflammation
Glucosamine + MSMcorn-derived glucosamine HClJointsInflammationRecovery
Collagen + MSM + GlucosaminepowderSkinJointsHair & nailsBones
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence

Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.

Combination check

Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.

Check Glucosamine with others

Which supplements do you actually need?

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From the same group

AlfalfaNo evidenceAndrographisWeak evidenceAroniaWeak evidenceBarley grassWeak evidenceBee pollenWeak evidenceBeef organs (desiccated)Weak evidence
Important notice

This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.