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Sleep & calmWeak evidence

Apigenin

Also known as: chamomile extract

Apigenin is a flavonoid from chamomile, parsley and celery that binds to calming receptors in the brain. Direct human studies with pure apigenin are very few.

What it is used for

  • Sleep – weak evidence (mainly for chamomile extract)
  • Mild anxiety (chamomile extract) – weak evidence
  • Longevity and NAD+ – laboratory evidence only

Forms and how they differ

apigenin from chamomile extract

standardised for apigenin content

chamomile tea

gentle natural source at a lower dose

When to take it

In the evening 30–60 minutes before bed.

Pairs well with

Works well with magnesium and L-theanine.

Do not combine / separate

Use caution with sleeping pills, sedatives and blood thinners.

Watch out for

Not recommended in pregnancy or breastfeeding due to lack of data. If you are allergic to the daisy family (ragweed, mugwort), have a hormone-sensitive condition, liver disease or take medicines, consult your doctor.

Safety

Long-term safety of higher doses has not been studied. Do not exceed the label dose.

Practical tip

A cup of chamomile tea as an evening ritual is a cheap start – the ritual itself helps too.

Products containing Apigenin 3

Apigenin chamomile extractchamomile extractSleepStressAntioxidant
Apigenin 300 mgchamomile flavone · 300 mg / capsuleSleepStressAntioxidant
ApigeninpowderSleepStressAntioxidant
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence

Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.

Combination check

Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.

Check Apigenin with others

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Important notice

This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.