When to take it
With a meal or protein, especially when the meal is low in protein.
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Also known as: leucine
Leucine is an essential branched-chain amino acid (BCAA) that acts as the main trigger for muscle protein synthesis. On its own it is not enough for muscle growth; the other amino acids are needed too.
bitter, poorly soluble; instantised mixes more easily
With a meal or protein, especially when the meal is low in protein.
Complete protein, EAAs, resistance training.
Little point adding it to a meal that already has enough quality protein.
Caution with kidney or liver disease and inherited amino acid disorders. Consult your doctor or pharmacist if you are pregnant, breastfeeding, have kidney or liver disease or take any medicines.
Do not exceed the label dose.
Leucine works best topping up a plant-based or smaller protein portion, not replacing it.
Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.
Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.
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This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.
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