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LongevityNo evidence

Longevity complex

Also known as: epigenetic complex, anti-ageing complex

Longevity or 'epigenetic' complexes typically combine NAD+ precursors (NMN, nicotinamide riboside), resveratrol, quercetin or fisetin, spermidine, trimethylglycine, curcumin, ergothioneine or B vitamins. Quality depends on the composition and doses on the label; there is no human evidence that they extend life or 'reverse epigenetic age'.

What it is used for

  • extending life or reducing 'biological age' – no reliable human evidence
  • individual ingredients (e.g. NAD+ precursors, spermidine) – weak evidence from small or animal studies

Forms and how they differ

blends listing mg of each ingredient

the only way to compare doses with studies

blends with B vitamins (folate, B12, B6)

these have EFSA-approved claims, e.g. for homocysteine

'proprietary' blends without doses

impossible to judge how much of each they contain

When to take it

In the morning with food, unless the label says otherwise.

Pairs well with

Exercise, sleep, a diet with enough vegetables and protein, and not smoking – the basics with the strongest evidence.

Do not combine / separate

Do not combine with other products containing the same ingredients (NMN, resveratrol, quercetin) without checking total doses; with blood thinners only after asking your doctor.

Watch out for

During pregnancy and breastfeeding, with cancer, liver or kidney disease, or if you take medicines (some ingredients affect liver enzymes), consult your doctor.

Safety

Long-term safety of such blends has not been studied; do not exceed the label dose.

Practical tip

When choosing, ask whether there is a study on the product itself – if not, judge only the ingredients and their doses.

Products containing Longevity complex 1

Longevity complexblendLongevityAntioxidantEnergy
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence

Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.

Combination check

Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.

Check Longevity complex with others

Which supplements do you actually need?

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Important notice

This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.