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Fénix Methode

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LongevityWeak evidence

Phosphatidylserine

Also known as: PS

Phosphatidylserine is a phospholipid and an important part of cell membranes, especially in the brain. Supplements are now made from soy or sunflower and are used for memory and coping with stress.

What it is used for

  • memory and thinking in older adults – weak evidence; older studies used bovine-brain PS, newer results are more modest
  • blunting the stress response (cortisol) – weak evidence from small studies
  • focus – weak evidence

Forms and how they differ

soy PS

most common source; choose another form if allergic to soy

sunflower PS

soy-free, suitable with soy allergy

PS with omega-3 (PS-DHA)

combination products; composition depends on the label

When to take it

With food; for stress and sleep, rather in the evening.

Pairs well with

Omega-3 (DHA), choline, B vitamins.

Do not combine / separate

Take care when combining with blood thinners and dementia medicines – consult your doctor.

Watch out for

Not suitable in pregnancy or breastfeeding due to lack of data. If you take medicines, consult your doctor or pharmacist.

Safety

Well tolerated at usual doses, occasionally causes digestive upset or insomnia; do not exceed the label dose.

Practical tip

Judge the effect only after 2–3 months of regular use – together with sleep and exercise.

Products containing Phosphatidylserine 1

Phosphatidylserine 100 mgsunflower PS · 100 mg / capsuleBrain & memoryStressFocus
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence

Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.

Combination check

Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.

Check Phosphatidylserine with others

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From the same group

Agaricus blazeiWeak evidenceAlpha-lipoic acidModerate evidenceAstaxanthinWeak evidenceCoenzyme Q10Moderate evidenceDNA protection blendNo evidenceErgothioneineWeak evidence
Important notice

This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.