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OtherWeak evidence

Butterbur

Also known as: Petasites hybridus

Butterbur is a herb whose root extract has been studied mainly for migraine prevention and hay fever. The raw plant contains pyrrolizidine alkaloids that damage the liver, so only extracts with these compounds removed should be used.

What it is used for

  • migraine prevention – older studies were encouraging, but it is no longer recommended in neurology guidelines because of liver concerns
  • hay fever – weak to moderate evidence for specific leaf extracts

Forms and how they differ

extract free of pyrrolizidine alkaloids (PA-free)

the only acceptable form

tea, tincture or raw plant

unsuitable – may contain liver-toxic alkaloids

When to take it

With food, as on the label; judge migraine prevention after several weeks.

Pairs well with

Magnesium and riboflavin for migraine prevention.

Do not combine / separate

Do not combine with other herbs or medicines that burden the liver, or with alcohol.

Watch out for

Do not use during pregnancy, breastfeeding, with liver disease or if allergic to daisy-family plants. If you take medicines, consult your doctor; with longer use, liver tests are advisable.

Safety

Do not exceed the label dose. Cases of liver injury have been reported; if you notice jaundice, dark urine or pain under the right ribs, stop and see a doctor.

Practical tip

Buy only products that explicitly state they are free of pyrrolizidine alkaloids (PA-free).

Products containing Butterbur 1

Butterbur + Feverfew 75 mgPA-free extract · 75 mg / capsuleInflammationImmunityJoints
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence

Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.

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Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.

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From the same group

AlfalfaNo evidenceAndrographisWeak evidenceAroniaWeak evidenceBarley grassWeak evidenceBee pollenWeak evidenceBeef organs (desiccated)Weak evidence
Important notice

This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.