When to take it
Before training or split during the day.
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Also known as: arginine, arginine AKG
Arginine is an amino acid the body uses to make nitric oxide, which supports blood flow. Taken orally, much of it is broken down in the gut and liver, so citrulline is often more effective.
basic form
popular in sport, benefits not convincingly shown
mixes of forms, often with ornithine; quality depends on the label
Before training or split during the day.
Citrulline, a protein-adequate diet.
Be careful with other substances lowering blood pressure.
Caution with blood pressure drugs, nitrates, erectile dysfunction drugs, recurrent herpes and after a heart attack. Consult your doctor or pharmacist if you are pregnant, breastfeeding, have kidney or liver disease or take any medicines.
Do not exceed the label dose.
If nitric oxide and blood flow are the goal, citrulline is usually the better choice.
Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.
Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.
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This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.
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