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Why do I have strong PMS and mood swings before my period?

In short

Premenstrual syndrome arises from the brain's sensitivity to natural changes in estrogen and progesterone in the second half of the cycle, amplified by stress, lack of sleep and diet. If your mood is severely affected before your period and it limits your life, it may be premenstrual dysphoric disorder, which can be treated.

Possible causes

  • Sensitivity to hormonal changes – it is not about "bad hormones" but a stronger brain response to their fall.
  • Serotonin – hormonal shifts affect serotonin, which regulates mood and cravings.
  • Stress and lack of sleep – amplify irritability, anxiety and sensitivity.
  • Blood sugar swings – sugar cravings and energy crashes worsen mood.
  • Nutrient deficiencies – low magnesium, vitamin D or iron may contribute to symptoms.
  • Conditions – thyroid disorders or depression often get worse before menstruation.

What to check

  • Symptom calendar – record mood and symptoms for 2–3 cycles; it helps distinguish PMS from other problems.
  • TSH, ferritin and vitamin D – common and easily addressed deficiencies.
  • Progesterone and estradiol – in the right phase of the cycle, as advised by your doctor.
  • Prolactin – if you also have tender breasts, an irregular cycle or nipple discharge.

What helps

  • Regular exercise – aerobic activity and strength work throughout the cycle ease symptoms.
  • Stable eating – protein, fibre and regular meals instead of sweets.
  • Less caffeine and alcohol – especially in the week before your period.
  • Sleep and rest – plan a less demanding schedule before your period.
  • Sensible supplements – magnesium or vitamin B6 are often tried; discuss the choice with your doctor.

When to see a doctor

See a doctor if before your period you experience deep sadness, hopelessness, severe anxiety or anger that disrupt relationships and work, if you have thoughts of self-harm, or if symptoms don't improve after your period. If you have thoughts of self-harm, seek help immediately.

Important notice

This answer is for education only and does not replace an examination or medical advice. It is not a diagnosis or treatment. Reference ranges differ between laboratories – always review your results with a doctor. With sudden, severe or worsening symptoms seek medical help; in an emergency call 112. Do not stop or change medication without your doctor.

Related blood markers

ProgesteroneOestradiol (E2)ProlactinTSHFerritinVitamin D (25-OH)Magnesium
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Answers are based on scientific literature and updated regularly.