Order protocol
Sleep & recovery Whole topic
Hormones & energy Whole topic
Metabolism & nutrition Whole topic
Brain & mind Whole topic
Longevity & body Whole topic
Women & family Whole topic
Basics & environment Whole topic
Biohacking & technology Whole topic
Fénix Methode

Tired of generic advice? A protocol built on your numbers.

Order protocol
All articles Every article is based on a chapter of the book NAVRHNUTÝ and peer-reviewed studies.
Biohacker score2 minutes – find out where your body holds you back Results checkNormal vs. optimal for your blood values Biological ageHow old your body is – from 9 blood values CalculatorsBMI, waist, protein, sleep, caffeine, VO2max Daily helperDaily routines, light, sleep and breathing on your phone My stackCheck supplements & medication + daily plan ChallengesSmall daily habits with reminders Fitness testVO2max, fitness age, strength and balance at home Biological twinAll your data in a 3D body What to get testedPrintable list of blood tests Sample protocolSee what you get E-numbers & sugarsWhat is on the label and what to avoid Online advisorAnswers to common questions about body and results SupplementsForms, timing and combination check RecipesMeals without hidden sugars or needless additives GlossaryBiohacking explained from A to Z Gift voucherGive health – the protocol or the book
← Back to the E-number overview
E627Caution

Disodium guanylate

Group: Flavour enhancers · in the book

Harm level3 of 5In moderation

In plain words

Disodium guanylate is a flavour enhancer almost always added together with MSG. You find it in crisps, instant noodles, stock cubes and seasoning mixes.

Where you find it: instant soups, crisps, stock cubes, seasoning mixes

Our recommendation

We recommend limiting it; people with gout or high uric acid should avoid it.

Possible risks and effects

  • Contains purines that turn into uric acid – unsuitable with gout and high uric acid.
  • Usually combined with MSG, boosting the overall umami effect.
  • May be of animal origin (e.g. fish), relevant for vegans.

For experts

The sodium salt of guanosine monophosphate (a nucleotide), obtained from yeast, by fermentation or from animal sources. It acts strongly in synergy with glutamate, so very small amounts suffice; it is not considered toxic at normal use, the main limitation being its purine content.

Check another E-number

More from this group

E620Glutamic acidE621Monosodium glutamate (MSG)E622Monopotassium glutamateE631Disodium inosinateE635Disodium 5'-ribonucleotidesE640Glycine

This information is educational and based on EFSA assessments and available studies; it does not replace medical advice. With allergies, intolerances or illness, follow your doctor’s advice.