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Calcium D-glucarate

Also known as: glucaric acid calcium salt

Calcium D-glucarate is the calcium salt of glucaric acid, which occurs in small amounts in fruit and vegetables (e.g. apples, broccoli, citrus). It is marketed for liver "detox" and oestrogen metabolism, but human evidence is lacking.

What it is used for

  • support for liver clearance of hormones and compounds (glucuronidation) – no human evidence, only lab and animal data
  • hormonal balance in women – no reliable evidence

Forms and how they differ

calcium D-glucarate capsules

the calcium content per dose is small; it is not a calcium source

When to take it

With food, as the label says.

Pairs well with

A diet rich in vegetables (especially cruciferous), fibre.

Do not combine / separate

If you take medicines processed by the liver via glucuronidation (including hormonal contraception), consult your doctor – it may theoretically affect their levels.

Watch out for

Not suitable in pregnancy or breastfeeding due to lack of data. With liver disease, hormone-sensitive conditions or when taking medicines, consult your doctor.

Safety

Long-term safety is poorly studied; do not exceed the label dose.

Practical tip

Regular fibre, vegetables and less alcohol do more for your liver and hormones than this supplement.

Products containing Calcium D-glucarate 1

Calcium D-glucarate 200 mgD-glucarate · 200 mg / capsuleLiverHormonesAntioxidant
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence

Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.

Combination check

Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.

Check Calcium D-glucarate with others

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Important notice

This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.