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DigestionWeak evidence

Artichoke

Also known as: globe artichoke, artichoke leaf extract, Cynara scolymus

Artichoke leaf extract contains bitter compounds and substances such as cynarin that stimulate bile production and flow. The European Medicines Agency recognises its traditional use for digestive complaints.

What it is used for

  • bloating, fullness and heaviness after meals – weak to moderate evidence, traditional use recognised by the EMA
  • a modest reduction in LDL cholesterol – weak evidence from smaller studies
  • liver support – weak evidence

Forms and how they differ

dry leaf extract

the most studied, standardised to cynarin or caffeoylquinic acids

1:3 tincture

contains alcohol, bitter taste

combinations with milk thistle and dandelion

typical liver blends – quality depends on the label

When to take it

Before or with a meal.

Pairs well with

Milk thistle, dandelion, gentian.

Do not combine / separate

With gallstones, do not combine with other substances that promote bile flow.

Watch out for

Not suitable with gallstones or bile duct obstruction. Avoid if allergic to daisy-family plants (chamomile, arnica). During pregnancy or breastfeeding, with kidney or liver disease, or when taking medicines, consult your doctor.

Safety

Generally well tolerated; occasional mild digestive upset. Do not exceed the label dose.

Practical tip

It works best as help with heavy, fatty meals – take it shortly before them.

Products containing Artichoke 4

Artichoke 450 mgleaf extract · 450 mg / capsuleLiverDigestion & gutHeart & vessels
Artichoke 500 mgleaf extract · 500 mg / capsuleLiverDigestion & gutHeart & vessels
ArtichoketinctureLiverDigestion & gutHeart & vessels
Milk thistle + Artichoke + Dandelion 300 mgsilymarin extract · 300 mg / capsuleLiverAntioxidantDigestion & gutHeart & vessels
How to read the evidence rating
Strong evidenceModerate evidenceWeak evidenceNo evidence

Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.

Combination check

Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.

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Important notice

This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.