When to take it
On an empty stomach or between meals.
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Also known as: natto enzyme
Nattokinase is an enzyme from natto, a traditional Japanese food made from fermented soybeans. It is studied for its ability to break down fibrin and support circulation, but human evidence is limited.
enzyme activity is given in fibrinolytic units
a food, also contains vitamin K2
On an empty stomach or between meals.
Exercise, a vegetable-rich diet.
Combining with blood thinners and aspirin.
It increases bleeding risk – not suitable with blood thinners, aspirin, clotting disorders or before surgery without consulting your doctor. Not recommended in pregnancy, breastfeeding, low blood pressure or soy allergy.
Do not exceed the dose stated on the label.
Nattokinase does not replace heart and circulation medicines – if you take them, consult your doctor.
Strong = several good human studies or official recommendations; moderate = promising but smaller studies; weak = few studies or mixed results; no evidence = claims not confirmed.
Select the supplements you take and, if relevant, your medicines. We show what interferes, what needs a time gap and what to watch out for.
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This information is educational and does not replace advice from a doctor or pharmacist. We do not give medicine dosages. Supplements are no substitute for a varied diet; if pregnant, breastfeeding, ill or on medication, consult a doctor first.
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